DTU BIOENGINEERING Department of Biotechnology and Biomedicine
Bygningstorvet
Building 116, room 118C
2800 Kgs. Lyngby
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The National Biologics Facility (NBF) and Bioneer A/S enters into a strategic collaboration with the aim of commercializing combined CRO services for mammalian expression of recombinant proteins.
Danish research into cell cultures and the development of proteins for biological pharmaceuticals—including for cancer treatment—is strengthened with new unit at DTU.
Researchers from DTU Biosustain have successfully produced mammalian cell lines (CHO) that can produce 1.2 g/L recombinant Alpha-1-antitrypsin proteins with human glycosylation profiles. This work can lead to better treatment of the genetic disease Alpha-1 antitrypsin deficiency and avoid dependency of blood donors.
What on earth have Chinese hamsters to do with medical drugs? Quite a lot as it turns out, as hamster cells can be programmed to sustainably produce anti-cancer drugs, among other things.