Publications

Characterization and Diversification of AraC/XylS Family Regulators Guided by Transposon Sequencing

Pearson, Allison N ; Incha, Matthew R ; Ho, Cindy N ; Schmidt, Matthias ; Roberts, Jacob B ; Nava, Alberto A ; Keasling, Jay D
in: ACS Synthetic Biology

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1021/acssynbio.3c00441

Chemoenzymatic indican for light-driven denim dyeing

Bidart, Gonzalo Nahuel ; Teze, David ; Jansen, Charlotte Uldahl ; Pasutto, Eleonora ; Putkaradze, Natalia ; Sesay, Anna Mamusu ; Fredslund, Folmer ; Lo Leggio, Leila ; Ögmundarson, Olafur ; Sukumara, Sumesh ; Qvortrup, Katrine ; Welner, Ditte Hededam
in: Nature Communications, vol: 15, issue: 1

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1038/s41467-024-45749-3

Codon-tRNA Coadaptation Bias for Identifying Strong Native Promoters in Komagataella phaffii

Kastberg, Louise La Barbera ; Petrov, Mykhaylo S. ; Strucko, Tomas ; Jensen, Michael K. ; Workman, Christopher T.
in: ACS Synthetic Biology, vol: 13, issue: 3, pages: 714-720

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1021/acssynbio.3c00567

Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals

Holtz, Maxence ; Acevedo-Rocha, Carlos G. ; Jensen, Michael K.
in: Current Opinion in Biotechnology, vol: 87

Type: Review (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1016/j.copbio.2024.103110

Commensal production of a broad-spectrum and short-lived antimicrobial peptide polyene eliminates nasal Staphylococcus aureus

Torres Salazar, Benjamin O. ; Dema, Taulant ; Schilling, Nadine A. ; Janek, Daniela ; Bornikoel, Jan ; Berscheid, Anne ; Elsherbini, Ahmed M.A. ; Krauss, Sophia ; Jaag, Simon J. ; Lämmerhofer, Michael ; Li, Min ; Alqahtani, Norah ; Horsburgh, Malcolm J. ; Weber, Tilmann ; Beltrán-Beleña, José Manuel ; Brötz-Oesterhelt, Heike ; Grond, Stephanie ; Krismer, Bernhard ; Peschel, Andreas
in: Nature Microbiology, vol: 9, issue: 1, pages: 200-213

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1038/s41564-023-01544-2

Complete biosynthesis of the potent vaccine adjuvant QS-21

Martin, Laetitia B.B. ; Kikuchi, Shingo ; Rejzek, Martin ; Owen, Charlotte ; Reed, James ; Orme, Anastasia ; Misra, Rajesh C. ; El-Demerdash, Amr ; Hill, Lionel ; Hodgson, Hannah ; Liu, Yuzhong ; Keasling, Jay D. ; Field, Robert A. ; Truman, Andrew W. ; Osbourn, Anne
in: Nature Chemical Biology, vol: 20, issue: 4, pages: 493-502

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1038/s41589-023-01538-5

Coupling High-Throughput and Targeted Screening for Identification of Nonobvious Metabolic Engineering Targets

Babaei, Mahsa ; Thomsen, Philip Tinggaard ; Pastor, Marc Cernuda ; Jensen, Michael Krogh ; Borodina, Irina
in: ACS Synthetic Biology

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1021/acssynbio.3c00396

Development of Corynebacterium glutamicum as a monoterpene production platform

Luckie, Bridget A. ; Kashyap, Meera ; Pearson, Allison N. ; Chen, Yan ; Liu, Yuzhong ; Valencia, Luis E. ; Romero, Alexander Carrillo ; Hudson, Graham A. ; Tao, Xavier B. ; Wu, Bryan ; Petzold, Christopher J. ; Keasling, Jay D.
in: Metabolic Engineering, vol: 81, pages: 110-122

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1016/j.ymben.2023.11.009

Differences in interaction of graphene/graphene oxide with bacterial and mammalian cell membranes

Lanai, Victor ; Chen, Yanyan ; Naumovska, Elena ; Pandit, Santosh ; Schröder, Elsebeth ; Mijakovic, Ivan ; Rahimi, Shadi
in: Nanoscale

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1039/d3nr05354g

Dilarmycins A-C, Calcium-Dependent Lipopeptide Antibiotics with a Non-canonical Ca(2+)-Binding Motif

Fernández-Pastor, Ignacio ; Ortiz-López, Francisco Javier ; Oves-Costales, Daniel ; Martín, Jesús ; Sánchez, Pilar ; Melguizo, Ángeles ; Reyes Gonzalez, Fernando ; Weber, Tilmann ; Genilloud, Olga
in: Organic Letters, vol: 26, issue: 7, pages: 1343–1347

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1021/acs.orglett.3c04195

Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion

Lachowicz, Jake C. ; Lennox-Hvenekilde, David ; Myling-Petersen, Nils ; Salomonsen, Bo ; Verkleij, Gijs ; Acevedo-Rocha, Carlos G. ; Caddell, Ben ; Gronenberg, Luisa S. ; Almo, Steven C. ; Sommer, Morten O.A. ; Genee, Hans J. ; Grove, Tyler L.
in: Journal of the American Chemical Society, vol: 146, issue: 3, pages: 1860-1873

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1021/jacs.3c05481

Discovery of nanobodies for the development of recombinant antivenoms

Burlet, Nick J. ; Ahmadi, Shirin ; Benard Valle, Melisa ; Thumtecho, Suthimon ; Ljungars, Anne ; Laustsen-Kiel, Andreas Hougaard
Presented at: 10th Alpbach Workshop on Affinity Proteomics

Type: Poster (Peer reviewed)

Status: Published | Year: 2024

Early-stage economic and environmental impact assessment for optimized bioprocess development

Etit, Deniz ; Ögmundarson, Ólafur ; Zhang, Jie ; Krogh Jensen, Michael ; Sukumara, Sumesh
in: Bioresource Technology, vol: 391, Part B

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1016/j.biortech.2023.130005

Edible mycelium bioengineered for enhanced nutritional value and sensory appeal using a modular synthetic biology toolkit

Maini Rekdal, Vayu ; van der Luijt, Casper R.B. ; Chen, Yan ; Kakumanu, Ramu ; Baidoo, Edward E.K. ; Petzold, Christopher J. ; Cruz-Morales, Pablo ; Keasling, Jay D.
in: Nature Communications, vol: 15, issue: 1

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1038/s41467-024-46314-8

Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis

Wang, Xinran ; Chen, Ningxin ; Cruz-Morales, Pablo ; Zhong, Biming ; Zhang, Yangming ; Wang, Jian ; Xiao, Yifan ; Fu, Xinnan ; Lin, Yang ; Acharya, Suneil ; Li, Zhibo ; Deng, Huaxiang ; Sun, Yuhui ; Bai, Linquan ; Tang, Xiaoyu ; Keasling, Jay D. ; Luo, Xiaozhou
in: Nature Metabolism

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1038/s42255-024-01024-9

Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice

Gencay, Yilmaz Emre ; Jasinskytė, Džiuginta ; Robert, Camille ; Semsey, Szabolcs ; Martínez, Virginia ; Petersen, Anders Østergaard ; Brunner, Katja ; de Santiago Torio, Ana ; Salazar, Alex ; Turcu, Iszabela Cristiana ; Eriksen, Melissa Kviesgaard ; Koval, Lev ; Takos, Adam ; Pascal, Ricardo ; Schou, Thea Staffeldt ; Bayer, Lone ; Bryde, Tina ; Johansen, Katja Chandelle ; Bak, Emilie Glad ; Smrekar, Frenk ; Doyle, Timothy B. ; Satlin, Michael J. ; Gram, Aurelie ; Carvalho, Joana ; Jessen, Lene ; Hallström, Björn ; Hink, Jonas ; Damholt, Birgitte ; Troy, Alice ; Grove, Mette ; Clube, Jasper ; Grøndahl, Christian ; Haaber, Jakob Krause ; van der Helm, Eric ; Zdravkovic, Milan ; Sommer, Morten Otto Alexander
in: Nature Biotechnology

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1038/s41587-023-01759-y

Engineering Saccharomyces cerevisiae for fast vitamin-independent aerobic growth

Ehrmann, Anja K. ; Wronska, Anna K. ; Perli, Thomas ; de Hulster, Erik A.F. ; Luttik, Marijke A.H. ; van den Broek, Marcel ; Carqueija Cardoso, Clara ; Pronk, Jack T. ; Daran, Jean Marc
in: Metabolic Engineering, vol: 82, pages: 201-215

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1016/j.ymben.2024.01.010

Engineering the carbon and redox metabolism of Paenibacillus polymyxa for efficient isobutanol production

Meliawati, Meliawati ; Volke, Daniel C. ; Nikel, Pablo I. ; Schmid, Jochen
in: Microbial Biotechnology, vol: 17, issue: 3

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1111/1751-7915.14438

Engineering yeast for the de novo synthesis of jasmonates

Tang, Hongting ; Lin, Shumin ; Deng, Jiliang ; Keasling, Jay D. ; Luo, Xiaozhou
in: Nature Synthesis

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1038/s44160-023-00429-w

Expanding the structural diversity of terpenes by synthetic biology approaches

Chen, Rong ; Wang, Ming ; Keasling, Jay D. ; Hu, Tianyuan ; Yin, Xiaopu
in: Trends in Biotechnology

Type: Review (Peer reviewed)

Status: Accepted/In press | Year: 2024 | DOI: https://doi.org/10.1016/j.tibtech.2023.12.006

Exploiting Genetic Interactions in Metabolic Engineering

Cachera, Paul Pierre-Yves Jean

Type: Ph.D. thesis

Status: Published | Year: 2024

Exploring Psychometric Determinants of Risk Perception, Preference and Climate Change Adaptation Behavior

von Bülow, Catharina Wolff ; Liu, Xiufeng ; Halsnæs, Kirsten
in: Journal

Type: Journal article (Peer reviewed)

Status: Submitted | Year: 2024

Exploring the microbial diversity of novel misos with metagenomics

Kothe, Caroline Isabel ; Rasmussen, Jacob Agerbo ; Mak, Sarah S.T. ; Gilbert, M. Thomas P. ; Evans, Joshua
in: Food Microbiology, vol: 117

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1016/j.fm.2023.104372

Exploring the secretome of Corynebacterium glutamicum ATCC 13032

Balasubramanian, Suvasini ; Køhler, Julie Bonne ; Jers, Carsten ; Jensen, Peter Ruhdal ; Mijakovic, Ivan
in: Frontiers in Bioengineering and Biotechnology, vol: 12

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.3389/fbioe.2024.1348184

ExpoSeq: simplified analysis of high-throughput sequencing data from antibody discovery campaigns

Sørensen, Christoffer V. ; Hofmann, Nils ; Rawat, Puneet ; Sørensen, Frederik V. ; Ljungars, Anne ; Greiff, Victor ; Laustsen, Andreas H. ; Jenkins, Timothy P.
in: Bioinformatics Advances, vol: 4, issue: 1

Type: Journal article (Peer reviewed)

Status: Published | Year: 2024 | DOI: https://doi.org/10.1093/bioadv/vbae020

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