Yaojun Tong

Yaojun Tong


Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark


Building 220, room 326F

2800 Kgs. Lyngby

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CRISPR/Cas-based genome engineering in natural product discovery

Tong, Yaojun ; Weber, Tilmann ; Lee, Sang Yup
in: Natural Product Reports, vol: 36, issue: 9, pages: 1225-1372

Type: Review (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1039/C8NP00089A


Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

Tong, Yaojun ; Whitford, Christopher M. ; Robertsen, Helene L. ; Blin, Kai ; Jørgensen, Tue S. ; Klitgaard, Andreas K. ; Gren, Tetiana ; Jiang, Xinglin ; Weber, Tilmann ; Lee, Sang Yup
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 116, issue: 41, pages: 20366-20375

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1073/pnas.1913493116


Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

Palazzotto, Emilia ; Tong, Yaojun ; Lee, Sang Yup ; Weber, Tilmann
in: Biotechnology Advances, vol: 37, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.biotechadv.2019.03.005


CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

Tong, Yaojun ; Robertsen, Helene Lunde ; Blin, Kai ; Weber, Tilmann ; Lee, Sang Yup
part of: Synthetic Metabolic Pathways, pages: 163-184, 2018

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1_11


New developments on actinomyces CRISPR tools

Tong, Yaojun
Presented at:
DTU Biosustain Annual Seminar 2017

Type: Conference abstract for conference

Status: Published     |    Year: 2017


CRISPR/CAS9 based engineering of actinomycetal genomes

Weber, Tilmann ; Tong, Yaojun ; Lee, Sang Yup
Patent no.: WO2016150855, Date: 2016-09-29

Type: Patent

Status: Published     |    Year: 2016


Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters

Tong, Yaojun ; Liu, Mei ; Zhang, Yu ; Liu, Xueting ; Huang, Ren ; Song, Fuhang ; Dai, Huanqin ; Ren, Biao ; Sun, Nuo ; Pei, Gang ; Bian, Jiang ; Jia, Xin-Ming ; Huang, Guanghua ; Zhou, Xuyu ; Li, Shaojie ; Zhang, Buchang ; Fukuda, Takashi ; Tomoda, Hiroshi ; Ōmura, Satoshi ; Cannon, Richard D. ; Calderone, Richard ; Zhang, Lixin
in: Synthetic and Systems Biotechnology, vol: 1, issue: 3, pages: 158-168

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1016/j.synbio.2016.10.001


Engineering of actinomycetes using CRISPR/Cas9 technologies

Weber, Tilmann ; Tong, Yaojun ; Blin, Kai ; Lee, Sang Yup
in: Planta Medica, vol: 81, issue: S01
Presented at:
9th Joint Meeting of AFERP, ASP, GA, JSP, PSE & SIF

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1055/s-0036-1596147


CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

Tong, Yaojun ; Charusanti, Pep ; Zhang, Lixin ; Weber, Tilmann ; Lee, Sang Yup
in: A C S Synthetic Biology, vol: 4, issue: 9, pages: 1020-1029

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    Year: 2015     |    DOI: https://doi.org/10.1021/acssynbio.5b00038