Tilmann Weber

Tilmann Weber

Professor

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark

Kemitorvet

Building 220, room 327D

2800 Kgs. Lyngby

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2019
 

Genome-Scale Metabolic Reconstruction of Actinomycetes for Antibiotics Production

Mohite, Omkar Satyavan ; Weber, Tilmann ; Kim, Hyun Uk ; Lee, Sang Yup
in: Biotechnology Journal, vol: 14, issue: 1

Type: Review (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/biot.201800377

  PDF

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

Tong, Yaojun ; Whitford, Christopher M. ; Robertsen, Helene L. ; Blin, Kai ; Jørgensen, Tue S. ; Klitgaard, Andreas K. ; Gren, Tetiana ; Jiang, Xinglin ; Weber, Tilmann ; Lee, Sang Yup
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 116, issue: 41, pages: 20366-20375

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1073/pnas.1913493116

  PDF

Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters

Blin, Kai ; Kim, Hyun Uk ; Medema, Marnix H. ; Weber, Tilmann
in: Briefings in Bioinformatics, vol: 20, issue: 4, pages: 1103-1113

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/bib/bbx146

 

Sequence-based classification of type II polyketide synthase biosynthetic gene clusters for antiSMASH

Villebro, Rasmus ; Shaw, Simon ; Blin, Kai ; Weber, Tilmann
in: Journal of Industrial Microbiology and Biotechnology, vol: 46, issue: 3-4, pages: 469-475

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1007/s10295-018-02131-9

 

Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

Palazzotto, Emilia ; Tong, Yaojun ; Lee, Sang Yup ; Weber, Tilmann
in: Biotechnology Advances, vol: 37, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.biotechadv.2019.03.005

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The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

Blin, Kai ; Pascal Andreu, Victòria ; de Los Santos, Emmanuel L C ; Del Carratore, Francesco ; Lee, Sang Yup ; Medema, Marnix H. ; Weber, Tilmann
in: Nucleic acids research, vol: 47, issue: D1, pages: D625–D630

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/nar/gky1060

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The Draft Whole-Genome Sequence of the Antibiotic Producer Empedobacter haloabium ATCC 31962 Provides Indications for Its Taxonomic Reclassification

Miess, Henrike ; Arlt, Patricia ; Apel, Alexander Kristian ; Weber, Tilmann ; Nieselt, Kay ; Hanssen, Friederike ; Czemmel, Stefan ; Nahnsen, Sven ; Gross, Harald
in: Microbiology Resource Announcements, vol: 8, issue: 45

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1128/mra.01120-19

2018
 

CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

Tong, Yaojun ; Robertsen, Helene Lunde ; Blin, Kai ; Weber, Tilmann ; Lee, Sang Yup
part of: Synthetic Metabolic Pathways, pages: 163-184, 2018

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1_11

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Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

Robertsen, Helene L. ; Musiol-Kroll, Ewa M. ; Ding, Ling ; Laiple, Kristina J. ; Hofeditz, Torben ; Wohlleben, Wolfgang ; Lee, Sang Yup ; Grond, Stephanie ; Weber, Tilmann
in: Scientific Reports, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41598-018-21507-6

 

Immense diversity found in secondary metabolite gene clusters in filamentous fungi and bacteria using comparative genomics

Vesth, Tammi ; Frisvad, Jens ; Kovács, Ákos ; Jelsbak, Lars ; Weber, Tilmann ; Baker, Scott E. ; Andersen, Mikael R.
Presented at:
17th European Conference on Computational Biology

Type: Poster (Peer reviewed)

Status: Published     |    Year: 2018