Michael Krogh Jensen

Michael Krogh Jensen

Senior Researcher

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark

Kemitorvet

Building 220, room 413F

2800 Kgs. Lyngby

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2019
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Engineered Reversal of Function in Glycolytic Yeast Promoters

Rajkumar, Arun S. ; Özdemir, Emre ; Lis, Alicia V. ; Schneider, Konstantin ; Qin, Jiufu ; Jensen, Michael K. ; Keasling, Jay D.
in: ACS Synthetic Biology, vol: 8, issue: 6, pages: 1462-1468

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acssynbio.9b00027

2018
 

An Orthogonal and pH-Tunable Sensor-Selector for Muconic Acid Biosynthesis in Yeast

Snoek, Tim ; Romero-Suarez, David ; Zhang, Jie ; Ambri, Francesca ; Skjoedt, Mette L. ; Sudarsan, Suresh ; Jensen, Michael K. ; Keasling, Jay D.
in: A C S Synthetic Biology, vol: 7, issue: 4, pages: 995-1003

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acssynbio.7b00439

 

Assembly and Multiplex Genome Integration of Metabolic Pathways in Yeast Using CasEMBLR

Jakočiūnas, Tadas ; Jensen, Emil D. ; Jensen, Michael Krogh ; Keasling, Jay D.
part of: Synthetic Metabolic Pathways, pages: 185-201, 2018

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1_12

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CasPER, a method for directed evolution in genomic contexts using mutagenesis and CRISPR/Cas9

Jakočiūnas, Tadas ; Pedersen, Lasse E. ; Lis, Alicia V. ; Jensen, Michael K. ; Keasling, Jay D.
in: Metabolic Engineering, vol: 48, pages: 288-296

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1016/j.ymben.2018.07.001

 

Design, Engineering, and Characterization of Prokaryotic Ligand-Binding Transcriptional Activators as Biosensors in Yeast

Ambri, Francesca ; Snoek, Tim ; Skjødt, Mette Louise ; Jensen, Michael Krogh ; Keasling, Jay D.
part of: Synthetic Metabolic Pathways, pages: 269-290, 2018, Springer

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1_17

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Design principles for nuclease-deficient CRISPR-based transcriptional regulators

Jensen, Michael K.
in: FEMS Yeast Research, vol: 18, issue: 4

Type: Review (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1093/femsyr/foy039

 

Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae

Krink-Koutsoubelis, Nicolas ; Loechner, Anne C. ; Lechner, Anna ; Link, Hannes ; Denby, Charles M. ; Vögeli, Bastian ; Erb, Tobias J. ; Yuzawa, Satoshi ; Jakociunas, Tadas ; Katz, Leonard ; Jensen, Michael K. ; Sourjik, Victor ; Keasling, Jay D
in: A C S Synthetic Biology, vol: 7, issue: 4, pages: 1105-1115

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acssynbio.7b00466

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Modular 5′-UTR hexamers for context-independent tuning of protein expression in eukaryotes

Petersen, Søren D. ; Zhang, Jie ; Lee, Jae S. ; Jakočiūnas, Tadas ; Grav, Lise M. ; Kildegaard, Helene F. ; Keasling, Jay D. ; Jensen, Michael K.
in: Nucleic acids research, vol: 46, issue: 21

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1093/nar/gky734

 

Synthetic Metabolic Pathways

Jensen, Michael Krogh ; Keasling, Jay

Type: Book (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1

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Use of prokaryotic transcriptional activators as metabolite biosensors in eukaryotic cells

Jensen, Michael Krogh ; Keasling, Jay ; Skjødt, Mette Louise ; Snoek, Tim
Patent no.: WO2018007526 , Date: 2018-01-11

Type: Patent

Status: Published     |    Year: 2018

2017
 

Easyclone-markerfree

Jessop Fabre, M. ; Jakociunas, T. ; Stovicek, V. ; Dai, Z. ; Jensen, M. K. ; Keasling, J. ; Borodina, I.
part of: Synthetic Biology Conference, SEED 2017, pages: 149-150, 2018, American Institute of Chemical Engineers
Presented at:
Synthetic Biology Conference: Engineering, Evolution, and Design, SEED 2017

Type: Article in proceedings (Peer reviewed)

Status: Published     |    Year: 2017

 

Genetically-encoded biosensors for yeast cell factory optimization

Ambri, Francesca ; Jensen, Michael K. ; Keasling, Jay D.
part of: Synthetic Biology Conference (SEED 2017) Engineering, Evolution, and Design , pages: 193-194, 2018, AIChE, American Institute of Chemical Engineers

Type: Conference abstract in proceedings (Peer reviewed)

Status: Published     |    Year: 2017

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Lighting up yeast cell factories by transcription factor-based biosensors

D'ambrosio, Vasil ; Jensen, Michael Krogh
in: FEMS Yeast Research, vol: 17, issue: 7

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1093/femsyr/fox076

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Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles

Lolle, Signe ; Greeff, Christiaan ; Petersen, Klaus ; Roux, Milena ; Jensen, Michael Krogh ; Bressendorff, Simon ; Rodriguez, Eleazar ; Sømark, Kenneth ; Mundy, John ; Petersen, Morten
in: Cell Host & Microbe, vol: 21, issue: 4, pages: 518-529

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1016/j.chom.2017.03.005

 

System-level perturbations of cell metabolism using CRISPR/Cas9

Jakociunas, Tadas ; Jensen, Michael Krogh ; Keasling, Jay
in: Current Opinion in Biotechnology, vol: 46, pages: 134-140

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1016/j.copbio.2017.03.014

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Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

Damgaard Jensen, Emil ; Ferreira, Raphael ; Jakociunas, Tadas ; Arsovska, Dushica ; Zhang, Jie ; Ding, Ling ; Smith, Justin D ; David, Florian ; Nielsen, Jens ; Jensen, Michael Krogh ; Keasling, Jay D
in: Microbial Cell Factories, vol: 16

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1186/s12934-017-0664-2

2016
 

CRISPR/Cas9 advances engineering of microbial cell factories

Jakociunas, Tadas ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Metabolic Engineering, vol: 34, pages: 44-59

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1016/j.ymben.2015.12.003

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EasyClone-MarkerFree

Fabre, Mathew Malcolm Jessop ; Jakociunas, Tadas ; Stovicek, Vratislav ; Dai, Z. ; Jensen, Michael Krogh ; Keasling, Jay ; Borodina, Irina
in: Biotechnology Journal, vol: 11, issue: 8, pages: 1110-1117

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1002/biot.201600147

 

Engineering an NADPH/NADPRedox Biosensor in Yeast

Zhang, Jie ; Sonnenschein, Nikolaus ; Pihl, Thomas Peter Boye ; Pedersen, Kasper Rud ; Jensen, Michael Krogh ; Keasling, Jay
in: A C S Synthetic Biology, vol: 5, issue: 12, pages: 1546–1556

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1021/acssynbio.6b00135

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Engineering of synthetic, stress-responsive yeast promoters

Rajkumar, Arun Stephen ; Liu, Guodong ; Bergenholm, David ; Arsovska, Dushica ; Kristensen, Mette ; Nielsen, Jens ; Jensen, Michael Krogh ; Keasling, Jay
in: Nucleic acids research, vol: 44, issue: 17

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1093/nar/gkw553

 

Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast

Skjødt, Mette Louise ; Snoek, Tim ; Kildegaard, Kanchana Rueksomtawin ; Arsovska, Dushica ; Eichenberger, M. ; Goedecke, T. J. ; Rajkumar, Arun Stephen ; Zhang, Jie ; Kristensen, Mette ; Lehka, B. ; Siedler, Solvej ; Borodina, Irina ; Jensen, Michael Krogh ; Keasling, Jay
in: Nature Chemical Biology, vol: 12, issue: 11, pages: 951-958

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1038/nchembio.2177

2015
 

Development of biosensors and their application in metabolic engineering

Zhang, Jie ; Jensen, Michael Krogh ; Keasling, Jay
in: Current Opinion in Chemical Biology, vol: 28

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1016/j.cbpa.2015.05.013

 

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

Jakociunas, Tadas ; Bonde, Ida ; Herrgard, Markus ; Harrison, Scott James ; Kristensen, Mette ; Pedersen, Lasse Ebdrup ; Jensen, Michael Krogh ; Keasling, Jay
in: Metabolic Engineering, vol: 28, pages: 213-222

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1016/j.ymben.2015.01.008

 

Recent applications of synthetic biology tools for yeast metabolic engineering

Jensen, Michael Krogh ; Keasling, Jay
in: FEMS Yeast Research, vol: 15, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1111/1567-1364.12185

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Transcriptome and genome size analysis of the venus flytrap

Jensen, Michael Krogh ; Vogt, Josef Korbinian ; Bressendorff, Simon ; Seguin-Orlando, Andaine ; Petersen, Morten ; Sicheritz-Pontén, Thomas ; Mundy, John
in: P L o S One, vol: 10, issue: 4

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1371/journal.pone.0123887

2014
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A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.

Lindemose, Søren ; Jensen, Michael Krogh ; de Velde, Jan Van ; O'Shea, Charlotte ; Heyndrickx, Ken S. ; Workman, Christopher ; Vandepoele, Klaas ; Skriver, Karen ; De Masi, Federico
in: Nucleic acids research, vol: 42, issue: 12, pages: 7681-7693

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2014     |    DOI: https://doi.org/10.1093/nar/gku502

2013
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ATAF1 transcription factor directly regulates abscisic acid biosynthetic gene NCED3 in Arabidopsis thaliana.

Jensen, Michael Krogh ; Lindemose, Søren ; De Masi, Federico ; Reimer, Julia J ; Nielsen, Michael ; Perera, Venura ; Workman, Christopher ; Turck, Franziska ; Grant, Murray R ; Mundy, John ; Petersen, Morten ; Skriver, Karen
in: FEBS Open Bio, vol: 3, pages: 321-327

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1016/j.fob.2013.07.006

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Structure, Function and Networks of Transcription Factors Involved in Abiotic Stress Responses.

Lindemose, Søren ; O'Shea, Charlotte ; Jensen, Michael Krogh ; Skriver, Karen
in: International Journal of Molecular Sciences (Online), vol: 14, issue: 3, pages: 5842

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.3390/ijms14035842

2012
 

Ca2+ Induces Spontaneous Dephosphorylation of a Novel P5A-type ATPase

Sorensen, Danny Mollerup ; Moller, Annette B. ; Jakobsen, Mia K. ; Jensen, Michael Krogh ; Vangheluwe, Peter ; Buch-Pedersen, Morten Jeppe ; Palmgren, Michael G.
in: Journal of Biological Chemistry, vol: 287, issue: 34, pages: 28336-28348

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1074/jbc.M112.387191

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Order by disorder in plant signaling

Kragelund, Birthe Brandt ; Jensen, Michael Krogh ; Skriver, Karen
in: Trends in Plant Science, vol: 17, issue: 11, pages: 625-632

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1016/j.tplants.2012.06.010

 

Regulation of basal resistance by a powdery mildew‐induced cysteine‐rich receptor‐like protein kinase in barley

Rayapuram, Cbgowda ; Jensen, Michael Krogh ; Maiser, Fabian ; Shanir, Johanna Vikgren ; Hornshøj, Henrik ; Rung, Jesper H. ; Gregersen, Per L. ; Schweizer, Patrick ; Collinge, David ; Lyngkjær, Michael F.
in: Molecular Plant Pathology, vol: 13, issue: 2, pages: 135-147

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1111/j.1364-3703.2011.00736.x

2011
 

Senescence-associated Barley NAC (NAM, ATAF1,2, CUC) Transcription Factor Interacts with Radical-induced Cell Death 1 through a Disordered Regulatory Domain

Kjaersgaard, Trine ; Jensen, Michael Krogh ; Christiansen, Michael ; Gregersen, Per L. ; Kragelund, Birthe Brandt ; Skriver, Karen
in: Journal of Biological Chemistry, vol: 286, issue: 41, pages: 35418-35429

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1074/jbc.M111.247221

2010
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NAC genes

Jensen, Michael Krogh ; Kjaersgaard, Trine ; Petersen, Klaus ; Skriver, Karen
in: Plant Signaling & Behavior, vol: 5, issue: 7, pages: 907-910

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.4161/psb.5.7.12099

 

The arabidopsis thaliana NAC transcription factor family

Jensen, Michael Krogh ; Kjaersgaard, Trine ; Nielsen, Michael M. ; Galberg, Pernille ; Petersen, Klaus ; O'shea, Charlotte ; Skriver, Karen
in: Biochemical Journal, vol: 426, issue: 2, pages: 183-196

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.1042/BJ20091234

2008
 

Transcriptional regulation by an NAC (NAM-ATAF1,2-CUC2) transcription factor attenuates ABA signalling for efficient basal defence towards Blumeria graminis f. sp hordei in Arabidopsis

Jensen, Michael Krogh ; Hagedorn, Peter ; De Torres-Zabala, Marta ; Grant, Murray R. ; Rung, Jesper H. ; Collinge, David B. ; Lyngkjær, Michael Foged
in: Plant Journal, vol: 56, issue: 6, pages: 867-880

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2008     |    DOI: https://doi.org/10.1111/j.1365-313X.2008.03646.x

2007
 

The Hv NAC6 transcription factor: a positive regulator of penetration resistance in barley and Arabidopsis

Jensen, Michael Krogh ; Rung, Jesper Henrik ; Gregersen, Per Langkjaer ; Gjetting, Torben ; Fuglsang, Anja Thoe ; Hansen, Michael ; Joehnk, Nina ; Lyngkjær, Michael Foged ; Collinge, David B.
in: Plant Molecular Biology, vol: 65, issue: 1-2, pages: 137-150

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2007     |    DOI: https://doi.org/10.1007/s11103-007-9204-5

2003
 

Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization

Greve, Krestine ; La Cour, Tanja ; Jensen, Michael Krogh ; Poulsen, Flemming M. ; Skriver, Karen
in: Biochemical Journal, vol: 371, issue: Pt 1, pages: 97-108

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2003