Yeast Cell Factories

Within this section, located at Chalmers University of Technology in Sweden, novel technologies are developed to advance the development of yeast cell factories. This involves:

  • Construction of detailed metabolic models 
  • Development of novel synthetic biology tools that will allow for rapid reconstruction of heterologous pathways in yeast 
  • Construction of new platform strains 
  • Development of yeast cells with an expanded substrate range, i.e. pentoses and carbohydrate polymers 
  • Development of yeast cells that can grow at adverse fermentation conditions, e.g. high temperatures or high product concentrations 
  • Advancement of a pipeline for use of directed evolution to identify metabolic engineering targets 


Jens Nielsen
Chief Scientific Officer
DTU Biosustain