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Synthetic Biology Tools for Yeast

In Synthetic Biology Tools for Yeast (SBTY) we focus on accelerating rational strain building and current labor-intensive trial and error engineering. Further, we focus on providing more tools for high-throughput screening of cell factories.

In order to accelerate rational strain building we design, assemble and characterise synthetic regulatory DNA parts and develop targeted multiplex genome editing tools for one-step biological transformation of cell factories.

To speed selection of best-performing cell factories we also develop biosensors for both small-molecule production and optimal precursor supplies required for bio-based chemical production.

All projects are aimed towards global industrial needs within design, build and screening of new yeast cell factories.


  • Small-molecule biosensors for high-throughput screening of cell factories 
  • Robust yeast cell factories with optimised precursor supply 
  • Targeted multiplex genome editing systems 
  • DNA parts characterisation and synthetic promoters for industrial fermentation

The Section is headed by Scientific Director, Professor Jay Keasling.


Jay Keasling
Scientific Director
DTU Biosustain


Michael Krogh Jensen
Senior Researcher
DTU Biosustain
+45 61 28 48 50