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2022
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Dual Effect: High NADH Levels Contribute to Efflux-Mediated Antibiotic Resistance but Drive Lethality Mediated by Reactive Oxygen Species

Arce-Rodríguez, Alejandro ; Pankratz, Debbie ; Preusse, Matthias ; Nikel, Pablo I ; Häussler, Susanne
in: mBio, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1128/mbio.02434-21

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Influence of oxygen levels on a genome reduced Pseudomonas putida strain

Jensen, Jesper W. ; Woodley, John M. ; Nikel, Pablo I. ; Junicke, Helena
Presented at:
7th Bioproscale symposium

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2022

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Oligomerization engineering of the fluorinase enzyme leads to an active trimer that supports synthesis of fluorometabolites in vitro

Kittila, Tiia-Riikka ; Calero Valdayo, Patricia Maria ; Fredslund, Folmer ; Lowe, Phillip T ; Tezé, David ; Nieto Domínguez, Manuel José ; O'Hagan, David ; Nikel, Pablo Ivan ; Welner, Ditte Hededam
in: Microbial Biotechnology, vol: 15, issue: 5, pages: 1622-1632

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1111/1751-7915.14009

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Synthetic metabolism for biohalogenation

Cros, Antonin ; Alfaro-Espinoza, Gabriela ; De Maria, Alberto ; Wirth, Nicolas T. ; Nikel, Pablo I.
in: Current Opinion in Biotechnology, vol: 74, pages: 180-193

Type: Review (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.copbio.2021.11.009

2021
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Cofactor Specificity of Glucose-6-Phosphate Dehydrogenase Isozymes in Pseudomonas putida Reveals a General Principle Underlying Glycolytic Strategies in Bacteria

Volke, Daniel Christoph ; Olavarría, Karel ; Nikel, Pablo Iván
in: mSystems, vol: 6, issue: 2, pages: 21

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1128/mSystems.00014-21

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Combinatorial pathway balancing provides biosynthetic access to 2-fluoro-cis,cis-muconate in engineered Pseudomonas putida

Wirth, Nicolas T. ; Nikel, Pablo I.
in: Chem Catalysis, vol: 1, issue: 6, pages: 1234-1259

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.checat.2021.09.002

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Design and Upscaling of Pseudomonas putida Fermentations for Robust Biomanufacturing

Jensen, Jesper W. ; Woodley, John M. ; Nikel, Pablo I. ; Junicke, Helena
Presented at:
6th BioProScale Symposium

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2021

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Engineering Native and Synthetic Pathways in Pseudomonas Putida for the Production of Tailored Polyhydroxyalkanoates

Mezzina, Mariela P. ; Manoli, María Tsampika ; Prieto, M. Auxiliadora ; Nikel, Pablo Ivan
in: Biotechnology Journal, vol: 16, issue: 3

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1002/biot.202000165