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2021
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antiSMASH 6.0: improving cluster detection and comparison capabilities

Blin, Kai ; Shaw, Simon ; Kloosterman, Alexander M ; Charlop-Powers, Zach ; van Wezel, Gilles P ; Medema, Marnix H ; Weber, Tilmann
in: Nucleic acids research

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1093/nar/gkab335

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A regulator based “semi-targeted” approach to activate silent biosynthetic gene clusters

Mingyar, Erik ; Mühling, Lucas ; Kulik, Andreas ; Winkler, Anika ; Wibberg, Daniel ; Kalinowski, Jörn ; Blin, Kai ; Weber, Tilmann ; Wohlleben, Wolfgang ; Stegmann, Evi
in: International Journal of Molecular Sciences , vol: 22, issue: 14

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/ijms22147567

 

A versatile biosensing platform coupling CRISPR–Cas12a and aptamers for detection of diverse analytes

Zhao, Xiangxiang ; Li, Shanshan ; Liu, Guang ; Wang, Zhong ; Yang, Zhiheng ; Zhang, Quanwei ; Liang, Mindong ; Liu, Jiakun ; Li, Zilong ; Tong, Yaojun ; Zhu, Guoliang ; Wang, Xinye ; Jiang, Lan ; Wang, Weishan ; Tan, Gao-Yi ; Zhang, Lixin
in: Science Bulletin, vol: 66, issue: 1, pages: 69-77

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.scib.2020.09.004

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A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing

Tong, Yaojun ; Jørgensen, Tue S ; Whitford, Christopher M ; Weber, Tilmann ; Lee, Sang Yup
in: Nature Communications, vol: 12, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41467-021-25541-3

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Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p

Tong, Yaojun ; Zhang, Jingyu ; Sun, Nuo ; Wang, Xiang Ming ; Wei, Qi ; Zhang, Yu ; Huang, Ren ; Pu, Yingying ; Dai, Huanqin ; Ren, Biao ; Pei, Gang ; Song, Fuhang ; Zhu, Guoliang ; Wang, Xinye ; Xia, Xuekui ; Chen, Xiangyin ; Jiang, Lan ; Wang, Shenlin ; Ouyang, Liming ; Xie, Ning ; Zhang, Buchang ; Jiang, Yuanying ; Liu, Xueting ; Calderone, Richard ; Bai, Fan ; Zhang, Lixin ; Alterovitz, Gil
in: Science Bulletin

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.scib.2020.12.035

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BiG-FAM: the biosynthetic gene cluster families database

Kautsar, Satria A ; Blin, Kai ; Shaw, Simon ; Weber, Tilmann ; Medema, Marnix H.
in: Nucleic acids research, vol: 49, issue: D1, pages: D490–D497

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1093/nar/gkaa812

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Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters

Gren, Tetiana ; Whitford, Christopher M. ; Mohite, Omkar S. ; Jørgensen, Tue S. ; Kontou, Eftychia E. ; Nielsen, Julie B. ; Lee, Sang Yup ; Weber, Tilmann
in: Scientific Reports, vol: 11, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41598-021-97571-2

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Complete genome sequence of Amycolatopsis sp. CA-230715, encoding a 35-module type I polyketide synthase

Jørgensen, Tue S. ; Gren, Tetiana ; Oves-Costales, Daniel ; Ortiz-López, Francisco Javier ; Carretero-Molina, Daniel ; González, Ignacio ; Blin, Kai ; Genilloud, Olga ; Weber, Tilmann
in: Microbiology Resource Announcements, vol: 10, issue: 38

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1128/MRA.00805-21

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Complete genome sequence of Streptomyces sp. strain CA-256286

Beck, Charlotte ; Gren, Tetiana ; Jørgensen, Tue S. ; González, Ignacio ; Román-Hurtado, Fernando ; Oves-Costales, Daniel ; Genilloud, Olga ; Weber, Tilmann
in: Microbiology Resource Announcements, vol: 10, issue: 22, pages: e00290-21

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1128/MRA.00290-21

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Complete genome sequence of the rare actinobacterium Kutzneria sp. Strain CA-103260

Jørgensen, Tue S. ; Gren, Tetiana ; Kontou, Eftychia E. ; González, Ignacio ; Román-Hurtado, Fernando ; Oves-Costales, Daniel ; Thomsen, Emil ; Charusanti, Pep ; Genilloud, Olga ; Weber, Tilmann
in: Microbiology Resource Announcements, vol: 10, issue: 30

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1128/MRA.00499-21