Publications Enzyme Engineering

Emerging approaches for biocatalysis supporting a sustainable future

Volke, Daniel C. ; Cros, Antonin ; Welner, Ditte H. ; Nikel, Pablo I.
in: Chem Catalysis, vol: 2, issue: 10, pages: 2400-2402

Type: Comment/debate (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.1016/j.checat.2022.10.006

Family 1 glycosyltransferases (GT1, UGTs) are subject to dilution-induced inactivation and low chemo stability toward their own acceptor substrates

Teze, David ; Bidart, Gonzalo Nahuel ; Welner, Ditte Hededam
in: Frontiers in Molecular Biosciences, vol: 9

Type: Journal article (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.3389/fmolb.2022.909659

Family 1 Glycosyltransferase UGT706F8 from Zea mays Selectively Catalyzes the Synthesis of Silibinin 7-Ο-β-D-Glucoside

Bidart, Gonzalo N. ; Putkaradze, Natalia ; Fredslund, Folmer ; Kjeldsen, Christian ; Ruiz, Ander Garralda ; Duus, Jens Ø. ; Teze, David ; Welner, Ditte H.
in: ACS Sustainable Chemistry and Engineering, vol: 10, issue: 16, pages: 5078-5083

Type: Journal article (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.1021/acssuschemeng.1c07593

In vivo fluorine biocatalysis

Nikel, Pablo I. ; Welner, Ditte H. ; Cros, Antonin ; Volke, Daniel C.
in: Chem Catalysis, vol: 2, issue: 10, pages: 2403-2405

Type: Comment/debate (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.1016/j.checat.2022.10.007

Oligomerization engineering of the fluorinase enzyme leads to an active trimer that supports synthesis of fluorometabolites in vitro

Kittila, Tiia-Riikka ; Calero Valdayo, Patricia Maria ; Fredslund, Folmer ; Lowe, Phillip T ; Tezé, David ; Nieto Domínguez, Manuel José ; O'Hagan, David ; Nikel, Pablo Ivan ; Welner, Ditte Hededam
in: Microbial Biotechnology, vol: 15, issue: 5, pages: 1622-1632

Type: Journal article (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.1111/1751-7915.14009

Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis

Del Giudice, Rita ; Putkaradze, Natalia ; dos Santos, Bruna Marques ; Hansen, Cecilie Cetti ; Crocoll, Christoph ; Motawia, Mohammed Saddik ; Fredslund, Folmer ; Laursen, Tomas ; Welner, Ditte Hededam
in: Plant Journal, vol: 111, issue: 6, pages: 1539-1549

Type: Journal article (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.1111/tpj.15904

Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

Haddad Momeni, Majid ; Fredslund, Folmer ; Bissaro, Bastien ; Raji, Olanrewaju ; Vuong, Thu V. ; Meier, Sebastian ; Nielsen, Tine Sofie ; Lombard, Vincent ; Guigliarelli, Bruno ; Biaso, Frédéric ; Haon, Mireille ; Grisel, Sacha ; Henrissat, Bernard Paul ; Welner, Ditte Hededam ; Master, Emma R. ; Berrin, Jean-Guy ; Abou Hachem, Maher
in: Nature Communications, vol: 12

Type: Journal article (Peer reviewed)

Status: Published | Year: 2021 | DOI: https://doi.org/10.1038/s41467-021-22372-0

Exploring the in Vitro Operating Window of Glycosyltransferase PtUGT1 from Polygonum tinctorium for a Biocatalytic Route to Indigo Dye

Petermeier, Philipp ; Fortuna, Cristina ; Hübschmann, Kathrine M. ; Bidart, Gonzalo N. ; Tørring, Thomas ; Teze, David ; Welner, Ditte H. ; Kara, Selin
in: ACS Sustainable Chemistry and Engineering, vol: 9, issue: 25, pages: 8497-8506

Type: Journal article (Peer reviewed)

Status: Published | Year: 2021 | DOI: https://doi.org/10.1021/acssuschemeng.1c01536

Natural product C-glycosyltransferases - a scarcely characterised enzymatic activity with biotechnological potential

Putkaradze, Natalia ; Tezé, David ; Fredslund, Folmer ; Welner, Ditte Hededam
in: Natural Product Reports, vol: 38, pages: 432-443

Type: Journal article (Peer reviewed)

Status: Published | Year: 2021 | DOI: https://doi.org/10.1039/d0np00040j

O-/N-/S-specificity in glycosyltransferase catalysis: From mechanistic understanding to engineering

Tezé, David ; Coines, Joan ; Fredslund, Folmer ; Dubey, Kshatresh D. ; Bidart, Gonzalo N. ; Adams, Paul D. ; Dueber, John E. ; Svensson, Birte ; Rovira, Carme ; Welner, Ditte Hededam
in: ACS Catalysis, vol: 11, issue: 3, pages: 1810-1815

Type: Letter (Peer reviewed)

Status: Published | Year: 2021 | DOI: https://doi.org/10.1021/acscatal.0c04171

Publications Enzyme Engineering

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