Publications - DTU Biosustain

Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production

Lennen, Rebecca M. ; Jensen, Kristian ; Mohammed, Elsayed T. ; Malla, Sailesh ; Börner, Rosa A. ; Chekina, Ksenia ; Özdemir, Emre ; Bonde, Ida ; Koza, Anna ; Maury, Jérôme ; Pedersen, Lasse E. ; Schöning, Lars Y. ; Sonnenschein, Nikolaus ; Palsson, Bernhard O. ; Sommer, Morten O. A. ; Feist, Adam M. ; Nielsen, Alex T. ; Herrgård, Markus J.
in: bioRxiv

Type: Journal article

Status: Submitted | Year: 2023 | DOI: https://doi.org/10.1101/634105

An engineered Escherichia coli Nissle 1917 increase the production of indole lactic acid in the gut

Dimopoulou, Chrysoula ; Bongers, Mareike ; Pedersen, Mikael ; Bahl, Martin I. ; Sommer, Morten O. A. ; Laursen, Martin F. ; Licht, Tine R.
in: FEMS Microbiology Letters, vol: 370

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1093/femsle/fnad027

Biocontainment strategies for in vivo applications of Saccharomyces boulardii

Hedin, Karl Alex ; Kruse, Vibeke ; Vazquez-Uribe, Ruben ; Sommer, Morten Otto Alexander
in: Frontiers in Bioengineering and Biotechnology, vol: 11

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.3389/fbioe.2023.1136095

Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice

Gencay, Yilmaz Emre ; Jasinskytė, Džiuginta ; Robert, Camille ; Semsey, Szabolcs ; Martínez, Virginia ; Petersen, Anders Østergaard ; Brunner, Katja ; de Santiago Torio, Ana ; Salazar, Alex ; Turcu, Iszabela Cristiana ; Eriksen, Melissa Kviesgaard ; Koval, Lev ; Takos, Adam ; Pascal, Ricardo ; Schou, Thea Staffeldt ; Bayer, Lone ; Bryde, Tina ; Johansen, Katja Chandelle ; Bak, Emilie Glad ; Smrekar, Frenk ; Doyle, Timothy B. ; Satlin, Michael J. ; Gram, Aurelie ; Carvalho, Joana ; Jessen, Lene ; Hallström, Björn ; Hink, Jonas ; Damholt, Birgitte ; Troy, Alice ; Grove, Mette ; Clube, Jasper ; Grøndahl, Christian ; Haaber, Jakob Krause ; van der Helm, Eric ; Zdravkovic, Milan ; Sommer, Morten Otto Alexander
in: Nature Biotechnology

Type: Journal article (Peer reviewed)

Status: Accepted/In press | Year: 2023 | DOI: https://doi.org/10.1038/s41587-023-01759-y

Kidney Transplant and Dialysis Patients Remain at Increased Risk for Succumbing to COVID-19

Weiss, Anne ; Hendrickx, Rodinde ; Stensgaard, Eva ; Jellingsø, Mads ; Sommer, Morten O.A.
in: Transplantation, vol: 107, issue: 5, pages: 1136-1138

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1097/TP.0000000000004462

Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals

Lennen, Rebecca M. ; Lim, Hyun Gyu ; Jensen, Kristian ; Mohammed, Elsayed T. ; Phaneuf, Patrick V. ; Noh, Myung Hyun ; Malla, Sailesh ; Börner, Rosa A. ; Chekina, Ksenia ; Özdemir, Emre ; Bonde, Ida ; Koza, Anna ; Maury, Jérôme ; Pedersen, Lasse E. ; Schöning, Lars Y. ; Sonnenschein, Nikolaus ; Palsson, Bernhard O. ; Nielsen, Alex T. ; Sommer, Morten O.A. ; Herrgård, Markus J. ; Feist, Adam M.
in: Metabolic Engineering, vol: 76, pages: 179-192

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1016/j.ymben.2023.01.012

Oral orismilast

Warren, Richard B. ; Strober, Bruce ; Silverberg, Jonathan I. ; Guttman, Emma ; Andres, Philippe ; Felding, Jakob ; Tutkunkardas, Deniz ; Kjøller, Kim ; Sommer, Morten O.A. ; French, Lars E.
in: Journal of the European Academy of Dermatology and Venereology, vol: 37, issue: 4, pages: 711-720

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1111/jdv.18812

Pangenome analysis reveals the genetic basis for taxonomic classification of the Lactobacillaceae family

Rajput, Akanksha ; Chauhan, Siddharth M. ; Mohite, Omkar S. ; Hyun, Jason C. ; Ardalani, Omid ; Jahn, Leonie J. ; Sommer, Morten OA ; Palsson, Bernhard O.
in: Food Microbiology, vol: 115

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1016/j.fm.2023.104334

Pharmacology of orismilast, a potent and selective PDE4 inhibitor

Silverberg, Jonathan I. ; French, Lars E. ; Warren, Richard B. ; Strober, Bruce ; Kjøller, Kim ; Sommer, Morten O.A. ; Andres, Philippe ; Felding, Jakob ; Weiss, Anne ; Tutkunkardas, Deniz ; Skak-Nielsen, Tine ; Guttman, Emma
in: Journal of the European Academy of Dermatology and Venereology, vol: 37, issue: 4, pages: 721-729

Type: Journal article (Peer reviewed)

Status: Published | Year: 2023 | DOI: https://doi.org/10.1111/jdv.18818

A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics

Malla, Sailesh ; van der Helm, Eric ; Darbani, Behrooz ; Wieschalka, Stefan ; Foerster, Jochen ; Borodina, Irina ; Sommer, Morten Otto Alexander
in: Frontiers in Microbiology, vol: 13

Type: Journal article (Peer reviewed)

Status: Published | Year: 2022 | DOI: https://doi.org/10.3389/fmicb.2022.855736