Mathias Uhlén

Mathias Uhlén

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark

2800 Kgs. Lyngby

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Publications
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2019
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A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome

Robinson, Jonathan L. ; Feizi, Amir ; Uhlén, Mathias ; Nielsen, Jens
in: Cell Reports, vol: 26, issue: 10, pages: 2622-2635

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.celrep.2019.02.025

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Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion

Lundqvist, Magnus ; Thalén, Niklas ; Volk, Anna Luisa ; Hansen, Henning Gram ; von Otter, Eric ; Nygren, Per-Åke ; Uhlén, Mathias ; Rockberg, Johan
in: Scientific Reports, vol: 9, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41598-018-36559-x

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SAMURAI (Solid-phase Assisted Mutagenesis by Uracil Restriction for Accurate Integration) for antibody affinity maturation and paratope mapping

Hu, Francis Jingxin ; Lundqvist, Magnus ; Uhlén, Mathias ; Rockberg, Johan
in: Nucleic acids research, vol: 47, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/nar/gkz050

 

Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics

Edfors, Fredrik ; Forsström, Björn ; Vunk, Helian ; Kotol, David ; Fredolini, Claudia ; Maddalo, Gianluca ; Svensson, Anne Sophie ; Boström, Tove ; Tegel, Hanna ; Nilsson, Peter ; Schwenk, Jochen M. ; Uhlén, Mathias
in: Journal of Proteome Research, vol: 18, issue: 7, pages: 2706-2718

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.jproteome.8b00924

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Systematic Development of Sandwich Immunoassays for the Plasma Secretome

Häussler, Ragna S. ; Bendes, Annika ; Iglesias, Maria Jesus ; Sanchez-Rivera, Laura ; Dodig-Crnković, Tea ; Byström, Sanna ; Fredolini, Claudia ; Birgersson, Elin ; Dale, Matilda ; Edfors, Fredrik ; Fagerberg, Linn ; Rockberg, Johan ; Tegel, Hanna ; Uhlén, Mathias ; Qundos, Ulrika ; Schwenk, Jochen M.
in: Proteomics, vol: 19, issue: 15

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/pmic.201900008

2018
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Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders

Hu, Francis Jingxin ; Volk, Anna-Luisa ; Persson, Helena ; Säll, Anna ; Borrebaeck, Carl ; Uhlén, Mathias ; Rockberg, Johan
in: New Biotechnology, vol: 45, pages: 80-88

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1016/j.nbt.2017.07.011

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Enhanced validation of antibodies for research applications

Edfors, Fredrik ; Hober, Andreas ; Linderbäk, Klas ; Maddalo, Gianluca ; Azimi, Alireza ; Sivertsson, Åsa ; Tegel, Hanna ; Hober, Sophia ; Szigyarto, Cristina Al Khalili ; Fagerberg, Linn ; von Feilitzen, Kalle ; Oksvold, Per ; Lindskog, Cecilia ; Forsström, Björn ; Uhlén, Mathias
in: Nature Communications, vol: 9

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41467-018-06642-y

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Surface Display of Small Affinity Proteins on Synechocystis sp Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1

Cengic, Ivana ; Uhlén, Mathias ; Hudson, Elton P.
in: Journal of Bacteriology, vol: 200, issue: 16

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1128/JB.00270-18

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Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

Danielsson, Frida ; Fasterius, Erik ; Sullivan, Devin ; Hases, Linnea ; Sanli, Kemal ; Zhang, Cheng ; Mardinoglu, Adil ; Al-Khalili, Cristina ; Huss, Mikael ; Uhlén, Mathias ; Williams, Cecilia ; Lundberg, Emma
in: OncoTarget, vol: 9, issue: 28, pages: 19730-19744

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.18632/oncotarget.24808

2017
 

Affibody scaffolds improve sesquiterpene production in Saccharomyces cerevisiae

Tippmann, Stefan ; Anfelt, Josefine ; David, Florian ; Rand, Jacqueline M. ; Siewers, Verena ; Uhlén, Mathias ; Nielsen, Jens ; Hudson, Elton Paul
in: A C S Synthetic Biology, vol: 6, issue: 1, pages: 19-28

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1021/acssynbio.6b00109