Jens Nielsen

Jens Nielsen

Chief Scientific Officer

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

CFB-S-Yeast Cell Factories

Technical University of Denmark

Kemitorvet

2800 Kgs. Lyngby

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2019
 

Synthetic Biology of Yeast

Liu, Zihe ; Zhang, Yueping ; Nielsen, Jens
in: Biochemistry, vol: 58, issue: 11, pages: 1511-1520

Type: Review (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.biochem.8b01236

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Identification of genes involved in shea butter biosynthesis from Vitellaria paradoxa fruits through transcriptomics and functional heterologous expression

Wei, Yongjun ; Ji, Boyang ; Siewers, Verena ; Xu, Deyang ; Halkier, Barbara Ann ; Nielsen, Jens
in: Applied Microbiology and Biotechnology, vol: 103, issue: 9, pages: 3727-3736

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1007/s00253-019-09720-3

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A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

Lu, Hongzhong ; Li, Feiran ; Sánchez, Benjamín J ; Zhu, Zhengming ; Li, Gang ; Domenzain, Iván ; Marcišauskas, Simonas ; Anton, Petre Mihail ; Lappa, Dimitra ; Lieven, Christian ; Beber, Moritz Emanuel ; Sonnenschein, Nikolaus ; Kerkhoven, Eduard J ; Nielsen, Jens
in: Nature Communications, vol: 10, issue: 1, pages: 3586

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41467-019-11581-3

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A gRNA-tRNA array for CRISPR-Cas9 based rapid multiplexed genome editing in Saccharomyces cerevisiae

Zhang, Yueping ; Wang, Juan ; Wang, Zibai ; Zhang, Yiming ; Shi, Shuobo ; Nielsen, Jens ; Liu, Zihe
in: Nature Communications, vol: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41467-019-09005-3

 

Antibiotic Lethality Is Impacted by Nutrient Availabilities: New Insights from Machine Learning

Nielsen, Jens
in: CELL, vol: 177, issue: 6, pages: 1373-1374

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.cell.2019.05.015

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A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome

Robinson, Jonathan L. ; Feizi, Amir ; Uhlén, Mathias ; Nielsen, Jens
in: Cell Reports, vol: 26, issue: 10, pages: 2622-2635

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.celrep.2019.02.025

 

Cell factory engineering for improved production of natural products

Nielsen, Jens
in: Natural Product Reports

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1039/c9np00005d

 

Construction of mini-chemostats for high-throughput strain characterization

Bergenholm, David ; Liu, Guodong ; Hansson, David ; Nielsen, Jens
in: Biotechnology and Bioengineering, vol: 116, issue: 5, pages: 1029-1038

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/bit.26931

 

Effects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptome

Bergman, Alexandra ; Vitay, Dóra ; Hellgren, John ; Chen, Yun ; Nielsen, Jens ; Siewers, Verena
in: FEMS Yeast Research, vol: 19, issue: 3

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/femsyr/foz027

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Engineering Saccharomyces cerevisiae cells for production of fatty acid-derived biofuels and chemicals

Hu, Yating ; Zhu, Zhiwei ; Nielsen, Jens ; Siewers, Verena
in: Biology Open, vol: 9, issue: 5

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1098/rsob.190049