Kai Xiong

Kai Xiong

Postdoc

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

CFB-S-CHO Cell Line Engineering And Design

Technical University of Denmark

Kemitorvet

Building 220, room 511F

2800 Kgs. Lyngby

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Publications
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2020
 

Awakening dormant glycosyltransferases in CHO cells with CRISPRa

Julie la Cour Karottki, Karen ; Hefzi, Hooman ; Xiong, Kai ; Shamie, Isaac ; Hansen, Anders Holmgaard ; Li, Songyuan ; Pedersen, Lasse Ebdrup ; Li, Shangzhong ; Lee, Jae Seong ; Min Lee, Gyun ; Kildegaard, Helene Faustrup ; Lewis, Nathan E.
in: Biotechnology and Bioengineering, vol: 117, issue: 2, pages: 593-598

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1002/bit.27199

2019
 

Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference

Xiong, Kai ; Marquart, Kim Fabiano ; Julie la Cour Karottki, Karen ; Li, Shangzhong ; Shamie, Isaac ; Lee, Jae Seong ; Gerling, Signe ; Yeo, Nan Cher ; Chavez, Alejandro ; Min Lee, Gyun ; Lewis, Nathan E ; Kildegaard, Helene Faustrup
in: Biotechnology and Bioengineering, vol: 116, issue: 7, pages: 1813-1819

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/bit.26969

2017
 

RNA-guided activation of pluripotency genes in human fibroblasts

Xiong, Kai ; Zhou, Yan ; Blichfeld, Kristian Aabo ; Hyttel, Poul ; Bolund, Lars ; Freude, Kristine Karla ; Luo, Yonglun
in: Cellular Reprogramming, vol: 19, issue: 3, pages: 189-198

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1089/cell.2017.0006

2016
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Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

Xiong, Kai ; Zhou, Yan ; Hyttel, Poul ; Bolund, Lars ; Freude, Kristine Karla ; Luo, Yonglun
in: Stem Cell Research, vol: 17, issue: 3, pages: 665-669

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1016/j.scr.2016.10.011

2015
 

PredcircRNA: computational classification of circular RNA from other long non-coding RNA using hybrid features

Pan, Xiaoyong ; Xiong, Kai
in: Molecular bioSystems, vol: 11, issue: 8, pages: 2219-2226

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1039/c5mb00214a

 

Wip1 knockout inhibits the proliferation and enhances the migration of bone marrow mesenchymal stem cells

Tang, Yiting ; Liu, Lan ; Sheng, Ming ; Xiong, Kai ; Huang, Lei ; Gao, Qian ; Wei, Jingliang ; Wu, Tianwen ; Yang, Shulin ; Liu, Honglin ; Mu, Yulian ; Li, Kui
in: Experimental Cell Research, vol: 334, issue: 2, pages: 310-322

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1016/j.yexcr.2015.03.018

2013
 

Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling

Xiong, Kai ; Li, Shanshan ; Zhang, Hongxiao ; Cui, Ye ; Yu, Debing ; Li, Yan ; Sun, Wenxing ; Fu, Yingying ; Teng, Yun ; Liu, Zhi ; Zhou, Xiaolong ; Xiao, Peng ; Li, Juan ; Liu, Honglin ; Chen, Jie
in: Molecular Biology Reports, vol: 40, issue: 7, pages: 4251-4256

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1007/s11033-013-2507-5

 

Two completely linked polymorphisms in the PPARG transcriptional regulatory region significantly affect gene expression and intramuscular fat deposition in the longissimus dorsi muscle of Erhualian pigs

Wang, H. ; Xiong, K. ; Sun, W. ; Fu, Y. ; Jiang, Z. ; Yu, D. ; Liu, H. ; Chen, J.
in: Animal Genetics, vol: 44, issue: 4, pages: 458-462

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1111/age.12025

2012
 

Stable silencing of β-lactoglobulin (BLG) gene by lentivirus-mediated RNAi in goat fetal fibroblasts

Zhang, Shumin ; Xiong, Kai ; Xie, Zhourui ; Nan, Wenting ; Liu, Honglin ; Chen, Jie
in: Genetics and Molecular Biology, vol: 35, issue: 3, pages: 680-685

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1590/S1415-47572012005000042