Research Assistant in Systems Biology/Bioinformatics

Thursday 08 Jul 21

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We are seeking a talented and driven Research Assistant to work on yeast systems biology as part of our projects on high throughput protein and genome engineering. The candidate will join the Cell Architecture Group (PI Ryan T. Gill) at the Novo Nordisk Foundation Center for Biosustainability (CFB) in Denmark.

The Cell Architecture Group is developing cellular engineering technologies based on high-throughput and multiplexed genome editing (CRISPR) for a wide range of downstream applications from industrial biotech to cell therapies. We operate under a design-build-test-learn philosophy and have a strong focus on commercialization of technology developed in the group. The CFB is part of the Technical University of Denmark and provides a world-class research environment with state-of-the-art facilities and advanced technologies with special emphasis on cell factory engineering and systems biology technologies.

Responsibilities and tasks
The candidate will focus on designing and implementing CRISPR-based libraries in yeast. This work leverages on previous technologies developed in our laboratory (https://doi.org/10.1038/nbt.3718 , https://doi.org/10.1021/acssynbio.0c00159 https://doi.org/10.1016/j.ymben.2018.07.007). The candidate will be expected to assist the research project forward by taking an active role in defining project goals, planning experiments, and analyzing data.

Specific tasks will include:

  • Design and implementation of CRISPR libraries
  • Genome sequencing/RNA-seq analysis
  • Assistance with wet lab experiments
  • Documentation of results in e-lab notebooks
  • Data analysis

Qualifications

  • Excellent problem solving skills
  • Experience with Python/ R/ MATLAB
  • Experience with molecular biology/ synthetic biology/ yeast genetics
  • Experience with Next-Generation Sequencing is a plus
  • Experience with gRNA library design is a plus
  • MSc degree or similar in Systems Biology/ Bioinformatics/ Bioengineering or similar

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice for the benefit of the surrounding community. We offer an interesting and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and an academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union.

Workplace and period of employment
The period of employment is limited to 1 year.

The place of employment is the DTU main campus in Kgs. Lyngby, Denmark.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Postdoc David Romero Suarez (darosu@biosustain.dtu.dk) or Professor Ryan T. Gill (rtg@biosustain.dtu.dk)

You can read more about the Novo Nordisk Foundation Center for Biosustainability on www.biosustain.dtu.dk.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Please submit your online application no later than 15 August 2021 (Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Diploma (MSc)
  • List of publications

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods.Learn more at www.biosustain.dtu.dk.  

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.