Lise Marie Grav

Lise Marie Grav

Postdoc

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

CFB-S-CHO Cell Line Engineering And Design

Technical University of Denmark

Kemitorvet

Building 220, room 508F

2800 Kgs. Lyngby

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2018
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Accelerated and Rational Design of Improved CHO Cell Factories

Grav, Lise Marie

Type: Ph.D. thesis

Status: Published     |    Year: 2018

 

Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation

Grav, Lise Marie ; Sergeeva, Daria ; Lee, Jae Seong ; Marín de Mas, Igor ; Lewis, Nathan E. ; Andersen, Mikael Rørdam ; Nielsen, Lars Keld ; Min Lee, Gyun ; Kildegaard, Helene Faustrup
in: A C S Synthetic Biology, vol: 7, issue: 9, pages: 2148-2159

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acssynbio.8b00140

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Modular 5′-UTR hexamers for context-independent tuning of protein expression in eukaryotes

Petersen, Søren D. ; Zhang, Jie ; Lee, Jae S. ; Jakočiūnas, Tadas ; Grav, Lise M. ; Kildegaard, Helene F. ; Keasling, Jay D. ; Jensen, Michael K.
in: Nucleic Acids Research, vol: 46, issue: 21

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1093/nar/gky734

2017
 

Application of CRISPR/Cas9 Genome Editing to Improve Recombinant Protein Production in CHO Cells

Grav, Lise Marie ; Julie la Cour Karottki, Karen ; Lee, Jae Seong ; Kildegaard, Helene Faustrup
part of: Heterologous Protein Production in CHO cells, pages: 101-118, 2017, Springer

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1007/978-1-4939-6972-2_7

2016
 

Accelerated Homology-Directed Targeted Integration of Transgenes in Chinese Hamster Ovary Cells Via CRISPR/Cas9 and Fluorescent Enrichment

Lee, Jae Seong ; Grav, Lise Marie ; Pedersen, Lasse Ebdrup ; Min Lee, Gyun ; Kildegaard, Helene Faustrup
in: Biotechnology and Bioengineering (Print), vol: 113, issue: 11, pages: 2518-2523

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1002/bit.26002

2015
 

CRISPR/Cas9-mediated genome engineering of CHO cell factories: application and perspectives

Lee, Jae Seong ; Grav, Lise Marie ; Lewis, Nathan E. ; Kildegaard, Helene Faustrup
in: Biotechnology Journal, vol: 10, issue: 7, pages: 979-994

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2015     |    DOI: https://doi.org/10.1002/biot.201500082

 

One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment.

Grav, Lise Marie ; Lee, Jae Seong ; Thomsen, Signe Gerling ; Beuchert Kallehauge, Thomas ; Hansen, Anders Holmgaard ; Kol, Stefan ; Min Lee, Gyun ; Pedersen, Lasse Ebdrup ; Kildegaard, Helene Faustrup
in: Biotechnology Journal, vol: 10, issue: 9, pages: 1446-1456

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    Year: 2015     |    DOI: https://doi.org/10.1002/biot.201500027


http://www.biosustain.dtu.dk/publications/person?id=68002&tab=2&qt=dtupublicationquery
19 JANUARY 2019