Gyun Min Lee

Gyun Min Lee

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

CFB-S-CHO Cell Line Engineering And Design

Technical University of Denmark

Kemitorvet

Building 220, room 506F

2800 Kgs. Lyngby

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Publications
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2019
 

Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines

Kim, Che Lin ; Min Lee, Gyun
in: Metabolic Engineering, vol: 52, pages: 57-67

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ymben.2018.11.003

2018
  PDF

Baicalein reduces oxidative stress in CHO cell cultures and improves recombinant antibody productivity

Kwang Ha, Tae ; Hansen, Anders Holmgaard ; Kol, Stefan ; Kildegaard, Helene Faustrup ; Min Lee, Gyun
in: Biotechnology Journal, vol: 13, issue: 3

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1002/biot.201700425

  PDF

Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies

Noh, Soo Min ; Shin, Seunghyeon ; Min Lee, Gyun
in: Scientific Reports, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41598-018-23720-9

 

Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation

Grav, Lise Marie ; Sergeeva, Daria ; Lee, Jae Seong ; Marín de Mas, Igor ; Lewis, Nathan E. ; Andersen, Mikael Rørdam ; Nielsen, Lars Keld ; Min Lee, Gyun ; Kildegaard, Helene Faustrup
in: A C S Synthetic Biology, vol: 7, issue: 9, pages: 2148-2159

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acssynbio.8b00140

 

Revealing key determinants of clonal variation in transgene expression in recombinant CHO cells using targeted genome editing

Lee, Jae Seong ; Park, Jin Hyoung ; Kwang Ha, Tae ; Samoudi, Mojtaba ; Lewis, Nathan E. ; Palsson, Bernhard O. ; Kildegaard, Helene Faustrup ; Min Lee, Gyun
in: A C S Synthetic Biology, vol: 7, issue: 12, pages: 2867-2878

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acssynbio.8b00290

 

Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine

Baek, Eric ; Lee, Jae Seong ; Min Lee, Gyun
in: Biotechnology and Bioengineering, vol: 115, issue: 9, pages: 2243-2254

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1002/bit.26777

2017

http://www.biosustain.dtu.dk/publications/person?id=112720&tab=2&qt=dtupublicationquery
19 JANUARY 2019