Postdoc in Computational Biology, Bioinformatics, Cheminformatics and Machine Learning

Center for Biosustainability
Wednesday 07 Feb 18

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We are seeking an extremely motivated postdoctoral researcher to join our highly international research center - The Novo Nordisk Foundation for Biosustainability, Technical University of Denmark, and become part of the Flux Optimization and BioAnalytics section headed by Prof. Douglas B. Kell.

The New BioAnalytics section at DTU Biosustain is working at the interface between computational biology, synthetic biology, metabolic engineering and bio-based products research, and aims to develop and implement innovative technologies to discover and improve bioprocesses.

Responsibilities and tasks
The successful candidate will focus on projects concerning the analysis, understanding and modelling of biochemical systems, especially from a cheminformatics point of views. The systems will be pertinent to both biotechnological production and to human health. A key task will be the production of suitable databases and standardised workflows. In addition, he/she will closely collaborate with other members, including bench scientists, as appropriate

Specific tasks:
  • Key role in the development and production of suitable workflows for computational biology, cheminformatics analysis, including bioinformatic and other data as appropriate
  • Particular focus on experimental metabolomics data (XC-MS)
  • Involvement in acquisition, integration and analysis of data from various sources (literature, omics, phenotypic)
  • Assistance in the automation (including automated analysis) of biochemical experiments
  • Lead on deep learning of multi-dimensional experimental design and protein-substrate interaction predictions
Other content of the position, e.g.:
  • Interaction with other computational modellers, including genome models, reaction network modellers.
  • Interaction with relevant experimental groups
  • cooperation with other institutes of DTU including Bio Engineering/Bio Informatics/Compute.
It is expected that the successful candidate will engage in collaborative efforts of the central DTU Biosustain software engineering team / DTU Biosustain iLoop, and will become part of a network with other colleagues at DTU working in computational biology and mass spectrometry-based metabolomics.

Qualifications
Candidates should have (or soon expect to obtain) a PhD degree or equivalent.

Further qualifications:
  • Extensive knowledge of bioinformaticscheminformatics, preferably within a workflow environment such as KNIME
  • Knowledge of bioinformatics highly desirable
  • Knowledge of XC-MS data deconvolution software strategies (e.g. Progenesis Qi) desirable
  • Candidates will be expected to have suitable programming experience
  • Experience of working in collaborative software projects
  • Experience in designing and implementing distributed software systems
  • Excellent python and shell programming skills
  • Knowledge and experience in using software testing frameworks
  • Knowledge of modern web-technologies.
  • Knowledge of general machine intelligence and analytics (optimisation, machine learning, clustering)
  • Interest and experience in modern data visualisation
  • Excellent scientific track record with good publications in the relevant field.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and an academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union.
The period of employment is 3 years.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Douglas Kell kelldb1@fastmail.fm

You can read more about the department at www.biosustain.dtu.dk

Application procedure
Please submit your online application no later than 21 February 2018 (local time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one PDF file. The file must include:
  • Application (cover letter)
  • CV
  • Views regarding research, based on the “Assessment” bullets
  • Documentation of previous teaching and research based on the “Assessment” bullets
  • List of publications
  • ORCID (see e.g. http://orcid.org/)
  • Diplomas (MSc/PhD)
Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Biosustain is an international research center of excellence developing next generation cell factories and bioprocesses for sustainable production of high-value chemical compounds as well as protein-based products. The center uses advanced metabolic engineering techniques and computational biology ensuring efficient and cost-effective design and construction processes.
The center’s activities are a balanced mix of basic and translational research, complemented by an emphasis on business development to facilitate commercialization of new cell factories and associated technologies. DTU Biosustain offers state-of-the-art research facilities and assembles world leaders in the field thus offering a unique platform providing excellent talent development and career opportunities.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 5,800 advance science and technology to create innovative solutions that meet the demands of society; and our 11,000 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.