PostDoc in Membrane Transport Proteins

Center for Biosustainability
Monday 04 Dec 17

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We are seeking a highly motivated and talented PostDoc to join the Yeast Metabolic Engineering group at the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) at the Technical University of Denmark.

The group headed by Dr. Irina Borodina focuses on metabolic engineering of yeast cell factories for sustainable production of chemicals from renewable feedstocks. We develop genetic engineering tools, which facilitate iterative cycles of strain development, and work on general methodology for accelerated rational strain design, based on systems biology-level data and modeling.

The position is in connection with a large research project YEAST-TRANS: Deciphering the transport mechanisms of small xenobiotic molecules in synthetic yeast cell factories. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 757384).

Responsibilities and tasks

  • Successful candidate will study the transport of industrially relevant xenobiotics in yeast. The methods will include high-throughput screening and characterization of transporter proteins using Xenopus expression system and solid-supported membrane electrophysiology
  • Transporter engineering will be applied for optimizing yeast host towards bio-based production of selected chemicals
  • The candidate will publish her/his research results in international peer-reviewed journals and present at conferences and seminars. Patenting activities can also be expected
  • The successful candidate will also contribute to researcher training and to the internal collaboration at the Center and external collaboration with international industrial and academic partners.
Candidates should have a PhD degree or equivalent.

Further qualifications:
  • PhD in Biotechnology, Bioengineering or Molecular Biology
  • Excellent track-record of publications and other scientific achievements
  • Hands-on expertise with Xenopus expression system
  • Hands-on expertise with electrophysiological methods for transporter characterization
  • Experience with writing research grants
  • Strong work ethic and motivation to succeed within a competitive research field
  • Team spirit and excellent collaboration skills
In the assessment of the candidates consideration will be given to
  • scientific production and research potential at international level
  • innovative skills and the ability to generate new ideas
  • the ability to communicate at all levels such as the provision of scientific advice to public sector authorities
  • an all-round experience basis, preferably including international experience
  • the ability to contribute to development of the department’s internal and external cooperation

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and an academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.

The post of research scientist is a permanent post as part of which the employee after a maximum of 4 years transfers to a position as senior research scientist provided that the employee is recommended for assessment and is deemed qualified.

You can read more about career paths at DTU here.

Workplace and period of employment
  • Kemitorvet 220, 2800 Kgs Lyngby
  • The employment is for 3 years

Further information
Further information may be obtained from Senior Scientist and Group Leader Irina Borodina, tel.: +45 4525 8020,

You can read more about DTU Biosustain on

Application procedure
Please submit your online application no later than 15 December 2017.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill in the online application form, and attach all your materials in English in one PDF file. The file must include:
  • Application (cover letter)
  • CV
  • Diploma (MSc/PhD – an official translation into English)
  • List of publications

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Biosustain is an international research center of excellence developing next generation cell factories and bioprocesses for sustainable production of high-value chemical compounds as well as protein-based products. The center uses advanced metabolic engineering techniques and computational biology ensuring efficient and cost-effective design and construction processes.
The center’s activities are a balanced mix of basic and translational research, complemented by an emphasis on business development to facilitate commercialization of new cell factories and associated technologies. DTU Biosustain offers state-of-the-art research facilities and assembles world leaders in the field thus, offering a unique platform providing excellent talent development and career opportunities.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 5,800 advance science and technology to create innovative solutions that meet the demands of society; and our 11,000 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.