Publications

Publikationer rss feed

2019
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A rapid methods development workflow for high-throughput quantitative proteomic applications

Chen, Yan ; Vu, Jonathan ; Thompson, Mitchell G. ; Sharpless, William A. ; Chan, Leanne Jade G. ; Gin, Jennifer W. ; Keasling, Jay D. ; Adams, Paul D. ; Petzold, Christopher J.
in: PLoS ONE, vol: 14, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1371/journal.pone.0211582

 

Are we there yet? How and when specific biotechnologies will improve human health

O'Day, Elizabeth ; Hosta-Rigau, Leticia ; Oyarzún, Diego A. ; Okano, Hideyuki ; de Lorenzo, Víctor ; von Kameke, Conrad ; Alsafar, Habiba ; Cao, Cong ; Chen, Guo-Qiang ; Ji, Weizhi ; Roberts, Richard J. ; Ronaghi, Mostafa ; Yeung, Karen ; Zhang, Feng ; Lee, Sang Yup
in: Biotechnology Journal, vol: 14, issue: 1, pages: 11

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/biot.201800195

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A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome

Robinson, Jonathan L. ; Feizi, Amir ; Uhlén, Mathias ; Nielsen, Jens
in: Cell Reports, vol: 26, issue: 10, pages: 2622-2635

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.celrep.2019.02.025

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Breaking the state-of-the-art in the chemical industry with new-to-Nature products via synthetic microbiology

Martinelli, Laura ; Nikel, Pablo Ivan
in: Microbial Biotechnology

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1111/1751-7915.13372

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Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion

Lundqvist, Magnus ; Thalén, Niklas ; Volk, Anna Luisa ; Hansen, Henning Gram ; von Otter, Eric ; Nygren, Per-Åke ; Uhlén, Mathias ; Rockberg, Johan
in: Scientific Reports, vol: 9, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41598-018-36559-x

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Collateral sensitivity constrains resistance evolution of the CTX-M-15 β-lactamase

Rosenkilde, Carola Elisa Heesemann ; Munck, Christian ; Porse, Andreas ; Linkevicius, Marius ; Andersson, Dan I. ; Sommer, Morten Otto Alexander
in: Nature Communications, vol: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41467-019-08529-y

 

Combining Pro-peptide Engineering and Multisite Saturation Mutagenesis to Improve the Catalytic Potential of Keratinase

Su, Chang ; Gong, Jin Song ; Sun, Yu Xin ; Qin, Jiufu ; Zhai, Shen ; Li, Heng ; Li, Hui ; Lu, Zhen Ming ; Xu, Zheng Hong ; Shi, Jin Song
in: A C S Synthetic Biology, vol: 8, issue: 2, pages: 425-433

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acssynbio.8b00442

 

Construction of mini-chemostats for high-throughput strain characterization

Bergenholm, David ; Liu, Guodong ; Hansson, David ; Nielsen, Jens
in: Biotechnology and Bioengineering

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1002/bit.26931

 

Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla

Vazquez-Uribe, Ruben ; van der Helm, Eric ; Misiakou, Maria-Anna ; Lee, Sang-Woo ; Kol, Stefan ; Sommer, Morten Otto Alexander
in: Cell Host & Microbe, vol: 25, issue: 2, pages: 233-241

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.chom.2019.01.003

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DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression

Yang, Laurence ; Ebrahim, Ali ; Lloyd, Colton J. ; Saunders, Michael A. ; Palsson, Bernhard
in: BMC Systems Biology, vol: 13, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1186/s12918-018-0675-6

 

Engineering glucose metabolism of escherichia coli under nitrogen starvation

Chubukov, Victor ; Desmarais, John James ; Wang, George ; Chan, Leanne Jade G. ; Baidoo, Edward E.K. ; Petzold, Christopher J. ; Keasling, Jay D. ; Mukhopadhyay, Aindrila
in: n p j Systems Biology and Applications, vol: 3, issue: 1

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1038/npjsba.2016.35

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Evolutionary highways to persistent bacterial infection

Bartell, Jennifer ; Sommer, Lea M. ; Haagensen, Janus Anders Juul ; Loch, Anne ; Espinosa Portero, Rocio ; Molin, Søren ; Johansen, Helle Krogh
in: Nature Communications, vol: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41467-019-08504-7

 

Evolving metabolism of 2,4-dinitrotoluene triggers SOS-independent diversification of host cells

Akkaya, Özlem ; Nikel, Pablo I. ; Pérez-Pantoja, Danilo ; de Lorenzo, Víctor
in: Environmental Microbiology, vol: 21, issue: 1, pages: 314-326

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1111/1462-2920.14459

 

Fructo-oligosaccharides (FOS) production by fungal submerged culture using aguamiel as a low-cost by-product

Muñiz-Márquez, Diana B. ; Teixeira, José A. ; Mussatto, Solange I. ; Contreras-Esquivel, Juan C. ; Rodríguez-Herrera, Raúl ; Aguilar, Cristóbal N.
in: L W T- Food Science and Technology, vol: 102, pages: 75-79

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.lwt.2018.12.020

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Genome editing of lactic acid bacteria: opportunities for food, feed, pharma and biotech

Börner, Rosa A. ; Kandasamy, Vijayalakshmi ; Axelsen, Amalie M. ; Nielsen, Alex T. ; Bosma, Elleke F.
in: F E M S Microbiology Letters, vol: 366, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/femsle/fny291

 

Harnessing xylose pathways for biofuels production

Li, Xiaowei ; Chen, Yun ; Nielsen, Jens
in: Current Opinion in Biotechnology, vol: 57, pages: 56-65

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.copbio.2019.01.006

 

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Bergman, Alexandra ; Hellgren, John ; Moritz, Thomas ; Siewers, Verena ; Nielsen, Jens ; Chen, Yun
in: Microbial Cell Factories

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1186/s12934-019-1072-6

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Meta synthetic biology: controlling the evolution of engineered living systems

Nørholm, Morten H. H.
in: Microbial Biotechnology, vol: 12, issue: 1, pages: 35-37

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1111/1751-7915.13350

 

Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines

Kim, Che Lin ; Min Lee, Gyun
in: Metabolic Engineering, vol: 52, pages: 57-67

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ymben.2018.11.003

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Improving Reproducibility in Synthetic Biology

Jessop-Fabre, Mathew M. ; Sonnenschein, Nikolaus
in: Frontiers in Bioengineering and Biotechnology, vol: 7

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.3389/fbioe.2019.00018

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Integration of enzymatic data in Bacillus subtilis genome-scale metabolic model improves phenotype predictions and enables in silico design of poly-γ-glutamic acid production strains

Massaiu, Ilaria ; Pasotti, Lorenzo ; Sonnenschein, Nikolaus ; Rama, Erlinda ; Cavaletti, Matteo ; Magni, Paolo ; Calvio, Cinzia ; Herrgård, Markus J.
in: Microbial Cell Factories, vol: 18

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1186/s12934-018-1052-2

 

Isolation and physicochemical characterization of different lignin streams generated during the second-generation ethanol production process

Castro, Rafael C.A. ; Ferreira, Isabela S. ; Roberto, Inês C. ; Mussatto, Solange I.
in: International Journal of Biological Macromolecules, vol: 129, pages: 497-510

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ijbiomac.2019.01.148

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Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

Ma, Tian ; Shi, Bin ; Ye, Ziling ; Li, Xiaowei ; Liu, Min ; Chen, Yun ; Xia, Jiang ; Nielsen, Jens ; Deng, Zixin ; Liu, Tiangang
in: Metabolic Engineering, vol: 52, pages: 134-142

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ymben.2018.11.009

 

NetSurfP-2.0: Improved prediction of protein structural features by integrated deep learning

Klausen, Michael Schantz ; Jespersen, Martin Closter ; Nielsen, Henrik ; Jensen, Kamilla Kjærgaard ; Jurtz, Vanessa Isabell ; Sønderby, Casper Kaae ; Sommer, Morten Otto Alexander ; Winther, Ole ; Nielsen, Morten ; Petersen, Bent ; Marcatili, Paolo
in: Proteins: Structure, Function, and Bioinformatics

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2019     |    DOI: https://doi.org/10.1002/prot.25674